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Being the knowing biologists that we are (ha!), we thought cedar-apple-rust fungus, took pictures, and noticed the same fungus on other junipers in the Garden.
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It's a fungus, to be sure, maybe a Gymnosporangium spp. -- I'll need to have my friend Meg, who's the Plant Diagnostician at the CU Plant Problem Clinic take a look!
It's definitely striking!